As a researcher I like to keep up with all of the latest studies of nutritional medicine in mental health, and this weeks not an exception.

What’s this study show?

You’ll find below a study which shows that in menopause women, omega 3 can help up to 70% of those with depression. This can happen in as little as 8 weeks! It’s quite astounding. Check it out below.

How can you get some omega 3 supplementation (at the right dose)?

I’ll have a blog post soon that will tell you the right doses of omega 3 for depression and what brand I use with patients that you can get for yourself. My book also provides you with the information you need, and you can get it here.

Omega 3 supplementation can help you break free from depression. It’s not the only natural supplement that can help- if you want to find out about other alternatives download my free report by visiting

All the best. Talk to you again soon.


Dr Janelle Sinclair

Omega-3 fatty acids for major depressive disorder associated with the menopausal transition: a preliminary open trial.

Menopause. 2011 Mar;18(3):279-84.

Freeman MP, Hibbeln JR, Silver M, Hirschberg AM, Wang B, Yule AM, Petrillo LF, Pascuillo E, Economou NI, Joffe H, Cohen LS.


OBJECTIVES: : We sought to obtain preliminary data regarding the efficacy of omega-3 fatty acids for major depressive disorder associated with the menopausal transition. Secondary outcomes were assessed for vasomotor symptoms (or hot flashes).

METHODS: : After a single-blind placebo lead-in, participants received 8 weeks of treatment with open-label omega-3 fatty acid capsules (eicosapentaenoic acid and docosahexaenoic acid, 2 g/d). The Montgomery-Asberg Depression Rating Scale (MADRS) was the primary outcome measure. Hot flashes were monitored prospectively using daily diaries and the Hot Flash Related Daily Interference Scale. Blood samples for plasma pretreatment and posttreatment essential fatty acid assays were obtained. Because of the small sample size, data were analyzed using nonparametric techniques.

RESULTS: : Of 20 participants treated with omega-3 fatty acids, 19 (95%) completed the study. None discontinued because of adverse effects. The pretreatment and final mean MADRS scores were 24.2 and 10.7, respectively, reflecting a significant decrease in MADRS scores (P < 0.0001). The response rate was 70% (MADRS score decrease of ?50%), and the remission rate was 45% (final MADRS score of ?7). Responders had significantly lower pretreatment docosahexaenoic acid levels than nonresponders did (P = 0.03). Hot flashes were present in 15 (75%) participants. Among those with hot flashes at baseline, the number of hot flashes per day improved significantly from baseline (P = 0.02) and Hot Flash Related Daily Interference Scale scores decreased significantly (P = 0.006).

CONCLUSIONS: : These data support further study of omega-3 fatty acids for major depressive disorder and hot flashes in women during the menopausal transition.