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Archive for October, 2010

Hi there.

I thought I’d update you with what’s going on in my life. Yesterday I spoke with a group of psychologists about the physical imbalances that can lead to depression. A planned 30 minute session with them turned into 90 minutes!! (Because they had so many questions and were so interested in what I had to share).

What I Taught The Psychologists

During my time with them in which we discussed the physical causes of depression that so often go overlooked I briefly shared about hormones, toxins,  histamine/methylation imbalances and the mauve factor. They were especially intrigued about the hormonal imbalances so I thought I’d share a little about them here today.

Something they weren’t aware of was that all sex hormones (testosterone, estrogen, progesterone etc) are made out of cholesterol, and they were all very similar molecules. Testosterone is actually converted in the body to estrogen. Because sex hormones are made from cholesterol we need to have enough cholesterol in our diets so that our hormones are able to be produced.

Eating Disorders, Hormonal Imbalances & Mood Problems

When I brought up this fact, they asked a very interesting question about eating disorders and hormones. They asked- If someone has an eating disorder or even has just believed the myth about all fats being bad for you (and are on a low fat diet), would this affect their hormones levels? And will the decreased hormone levels then lead to further problems with mood?

The simple answer is yes -very very likely. If you don’t have the right ‘building blocks’ (cholesterol) in the body you can’t make your hormones. And the fact is that hormonal deficiencies (like progesterone and estrogen) can increase depression and anxiety.

Interesting Research

There’s some interesting research on this topic that you can find here http://www.ncbi.nlm.nih.gov/pubmed/20860875 It actually talks about how estrogen therapy might be a novel strategy for the treatment of anorexia. It also mentions how estrogen can help major depression.

If you’d like to find out whether you have symptoms of an estrogen deficiency (or other hormonal imbalances) and how to treat it naturally you can get a copy of my free questionnaire at www.breakingfreefromdepression.com/free-report.

Here’s my Key to Healing Depression and Anxiety

My key for healing your depression and anxiety today:

Find out whether it has a physical cause (it may not be able the way you think).

Hormonal imbalances, nutrient deficiencies, toxins and food allergies can give you depression and anxiety. To find out how you can diagnose them click here.

I hope and pray that this information will bring you freedom and assist you to break free from depression. All the best.

Janelle

Dr Janelle Sinclair

BSc, MSc, PhD (Biochemistry), NZNMA

Toxic exposure, depression and anxiety

Saturday, October 23rd, 2010

Over the next couple of weeks I thought that I would blog about some of the toxins that can cause depression, anxiety and other mental illness.

Toxins as a cause of depression and anxiety should not be disregarded!

In fact the involvement of toxins and chemicals in psychiatric disorders has been recently highlighted in the journal NeuroToxicology by Dr. Genuis. The scientific paper was entitled “Toxic causes of mental illness are overlooked.”

I think the title is a very good one, because even though its been known for over 300 years that toxins like mercury can lead to mental health problems- today it is still disregarded.

Today Let’s Look at the heavy metal Manganese

Most people know manganese as a mineral (like iron, iodine or selenium). This is true, and the body needs it in small amounts- it’s essential. It is an antioxidant, helps healthy digestion and formation of bones.

In large amounts however, manganese is toxic and is known as a heavy metal. That’s what we’re going to talk about today.

Manganese is Toxic and can cause Depression & Anxiety

Manganese is a heavy metal that can cause health concerns including irritability, mood changes, compulsive behaviors, and Parkinson Disease like tremors. A recent study investigating mood disorders and manganese exposure through welding showed alarming results. Those that had the highest past exposure to manganese were seven and a  half times more likely to be hostile, 2.6 times more likely to suffer from depression, and three times more likely to have anxiety. These symptoms were experienced even fourteen years after the workers last exposure to manganese.

Exposure to Manganese

You may be exposed to manganese through different occupations including mining, ore-processing, ferroalloy production, dry-cell battery factories, smelters, welders, and gas station attendants. In addition, you can be exposed through gasoline, contaminated soil and water, and living in close proximity to mining and other industries involving manganese.

If your depression or anxiety is caused by toxins, you can be healed by removing exposure to that chemical, and just as importantly detoxifying your body properly.

Join me next time to find out what types of toxins (and other occupations), can contribute to depression.

Toxins aren’t the only physical cause for depression and anxiety. To find out what hormonal imbalances, nutrient deficiencies and food allergies contribute to mental health disorders download a copy of my free depression report.

Talk to you again soon.

Dr Janelle Sinclair

Depression & Alcoholism- there underlying cause.

Monday, October 18th, 2010

I had an interesting question this week from one of my readers who had downloaded a free copy of my depression report.

She had received an email from me which explained a little bit of my story, and how I had come to be interested in natural medicine and eventually to write my book on depression.

A Little of My Story

In this email I explained how my father had struggled with food intolerances all of his life. Although he didn’t suffer from depression, he did struggle with behavioural problems as a child. I think he probably would have been labelled ADHD (Attention-deficit hyperactivity disorder) if he was a child today.

As an adult, my father suffered from bad headaches and muscle pain because of reactions to certain foods. The reason I discussed my father’s struggles, is that it taught me first hand that each of us are biochemically unique and that one person’s medicine can be another person’s poison. For my dad (and me) berries rich in antioxidants like blueberries, boysenberries and strawberries (which are other people’s medicine) were our poison – it gave us headaches and muscle pain.

What’s my Point?

But let’s get back to the point of this blog- to discuss a question I got this week from a reader. What was her question?

Q: Is there any alcoholism in my family?

The simple answer to this question is no. My father and his family were tee totallers because they were brought up in the Salvation Army Church who don’t drink alcohol.

Although my family hasn’t suffered from alcoholism, it was a good question from my reader. The reason I say this is that some of the same biochemical/physical causes for depression can also contribute to alcoholism.

Alcoholism & Depression

Many alcoholics are actually self medicating (and some people that only have 1 glass a night actually are too). You see there are physical imbalances that mean some people have the tendency to be anxious, or worry, or be sad for no real reason (or for only small reasons). This underlying anxiety or sadness may be the reason people turn to alcohol, which may be the only thing that they know can help ease their inner tension.

It’s a real shame that more people don’t find out this information, because when the physical cause (or causes) of depression and/or alcoholism is uncovered, there are supplements, dietary changes and hormones that can help them recover. The feelings of anxiety, worry, and sadness can be eased.

Is Alcoholism & Depression in Your Family?

If you are suffering from depression, and someone else in your family suffers from alcoholism (or there is a history of it in your family)- it’s very likely that they have the same root cause. I suggest that you get a copy of my free depression report which discusses the physical/biochemical causes of depression. When you read it take special note of the following physical/biochemical causes of depression (and alcoholism):

  • Sugar imbalances (reactive hypoglycemia)
  • The Mauve Factor (formerly known as kryptopyrroles)
  • Adrenal imbalances
  • Histamine imbalances.

Talk to you next time. I hope and pray that this information leads to freedom, peace and joy in your life, or the life of your loved one.

Sincerely

Dr Janelle Sinclair

BSc, MSc, PhD (Biochemistry), NZNMA

The Oral Contraceptive “Pill” & Your Depression

Monday, October 11th, 2010

Did you know that the oral contraceptive pill can be a cause of depression?

It’s not commonly known, but its really important, especially when you consider so many women are on it, and often for decades! Are you one of them?

I think the most insidious thing about the “Pill” and depression, is that the affect of the pill is slow. There may not be a clear relationship between the time you ‘went on’ the pill, and the onset of your depression or depressive symptoms. Why you may ask?

How The Oral Contraceptive Pill Can Cause Depression

If I first explain how the pill can cause depression, it’ll be easier for me to show you how it can ‘creep up on you’ and cause depression.

I should firstly say that I’m talking about the pill that contains estrogen specifically.

Here’s an excerpt from my book which explains it:

When copper is too high in the body it can lead to depression, lethargy, and a lack of energy. High levels of the estrogen hormone, which occurs during pregnancy and while taking the contraceptive pill, can lead to the build up of copper. That’s why many women experience depression during or after pregnancy, as well as when they’re on the oral contraceptive pill.

If you have postnatal depression, see the suggestions below about getting tested for copper.

If you take the oral contraceptive pill ask yourself “When did I start taking this medication in relation to the depression?” “Did the depressive symptoms begin after taking it?” (Note: Depression can begin months or years after starting the medication as it can take that long for your copper levels to build up.)

So did you get that? The estrogen in the pill increases copper in your body, and high copper is one of the causes for depression.

Note that it can take years for your copper levels to get so high that it causes problems for you. No wonder it’s often hard to figure out the causes of depression, ah?!

Are you looking at what could be causing your depression differently now? I hope so.

If you’re interested in finding out more about the other 20 physical causes for depression check out my free report at www.breakingfreefromdepression.com/free-report. I know that there will be other things in it that will surprise you! And if you’re a male reading this (good on you for getting this far), there’s heaps in the report that will be of interest to you to.

Best regards

Dr Janelle Sinclair (PhD Biochemistry)

PS It might take more than just stopping your pill to stop your depression. I don’t have time right now to explain how to lower your copper levels, but there are natural supplements that can do it.

Are Antidepressant Meds Effective?

Friday, October 8th, 2010

Hi There.

As you may know by now, this blog, my research and my book, talks about treating depression in a new way. A way that is individualized and seeks to find the physical or biochemical cause for the depression and treat it naturally.

I’m not against antidepressant medication- I know that for some people it is a life saver. What I disagree with is that most people do not have the physical causes for their depression investigated, before they are offered antidepressants. I personally think that when there are no immediate risks involved for the person in question, hormonal imbalances, nutrient deficiencies, food allergies and exposure to toxins should be investigated.

The Latest Research on Antidepressants

So today I thought I’d share a scientific study that was released a couple of months ago basically saying that ‘the current care for depression (antidepressants and cognitive therapy) needs to be reassessed’. The common belief that antidepressants and cognitive therapy are effective, may not be as true as most people (both public and physicians) think.

The abstract for this study is below, and is pretty technical- but the take home message is- “Antidepressant meds are only marginally more effective than placebo”.

If antidepressant medications aren’t effective, what do we do?

If you’re wondering what other options you’ve got to antidepressants, (or that you can use in combination with antidepressants), you’re in the right place. I’ve found out that there are over 20 different ways to treat depression effectively- the key is to find out what is causing the depression in the first place. If you want to find out more about it I’ve written a free report just for you. I know that you’ll find it interesting and most importantly helpful for finding healing for you.

All the best.

Dr Janelle Sinclair

Here’s the abstract from this scientific report:

Efficacy and effectiveness of antidepressants: current status of research. Psychother Psychosom. 2010;79(5):267-79.

Authors: Pigott HE, Leventhal AM, Alter GS, Boren JJ.

Abstract

BACKGROUND: This paper examines the current status of research on the efficacy and effectiveness of antidepressants.

METHODS: This paper reviews four meta-analyses of efficacy trials submitted to America’s Food and Drug Administration (FDA) and analyzes STAR*D (Sequenced Treatment Alternatives to Relieve Depression), the largest antidepressant effectiveness trial ever conducted.

RESULTS: Meta-analyses of FDA trials suggest that antidepressants are only marginally efficacious compared to placebos and document profound publication bias that inflates their apparent efficacy. These meta-analyses also document a second form of bias in which researchers fail to report the negative results for the pre-specified primary outcome measure submitted to the FDA, while highlighting in published studies positive results from a secondary or even a new measure as though it was their primary measure of interest. The STAR*D analysis found that the effectiveness of antidepressant therapies was probably even lower than the modest one reported by the study authors with an apparent progressively increasing dropout rate across each study phase.

CONCLUSIONS: The reviewed findings argue for a reappraisal of the current recommended standard of care of depression.

http://www.ncbi.nlm.nih.gov/pubmed/20616621 (here’s the original research- the complete article is available at that link too).

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